Two New Sesquiterpenoids from Solanum lyratum with Cytotoxic Activities
نویسندگان
چکیده
منابع مشابه
Anticancer activity of sesquiterpenoids extracted from Solanum lyratum via the induction of mitochondria-mediated apoptosis.
Sesquiterpenoids are a major type of compound found in Solanum lyratum (S. lyratum). The present study aimed to investigate whether sesquiterpenoids from S. lyratum demonstrated cytotoxicity against the MCF-7, HCT-8, A-549, SGC-7901 and BEL-7402 cell lines, and the mechanism of solajiangxin H and lyratol D, which exhibited high cytotoxicity against SGC-7901 cells (half maximal inhibitory concen...
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Three new sesquiterpenoids, lubiminoic acid, epilubiminoic acid and aethione, and six known sesquiterpenoids, solavetivone, 3beta-hydroxysolavetivone, 13-hydroxysolavetivone, anhydro-beta-rotunol, epilubimin and lubimin, were isolated from roots of S. aethiopicum L. Their structures were elucidated by spectroscopic data.
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Two new daucane sesquiterpenoids 1β,2β-epoxy-10(H)α-dauca-11(12)-ene-7α,14-diol and 1α,2α-epoxy-10(H)α-dauca-11(12)-ene-7α,14-diol were isolated from the plateau medicinal plant Daphne aurantiaca Diels. (Thymelaeceae). Their structures were elucidated by 1D and 2D NMR spectroscopy, as well as HR-ESI-MS data.
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ژورنال
عنوان ژورنال: Chemical and Pharmaceutical Bulletin
سال: 2009
ISSN: 0009-2363,1347-5223
DOI: 10.1248/cpb.57.408